All functions

cyto_check()

Check if input to cytoxxx function have errors

cytoflexmix()

Logistic mixture regression

cytoglm()

Fit GLM with bootstrap resampling

cytoglmm()

Fit GLMM with method of moments

cytogroup()

Group-specific fixed effects model

cytostab()

Evaluate parameter stability with respect to gating sheme

generate_data()

Generate dataset for vignettes and simulation studies

glmm_moment()

Generalized linear mixed model with maximum likelihood

is_unpaired()

Check if samples match or paired on condition

plot(<cytoflexmix>)

Plot all components of mixture regression

plot(<cytoglm>)

Plot bootstraped coefficients

plot(<cytoglmm>)

Plot fixded coefficients of random effects model

plot(<cytogroup>)

Plot fixded coefficients of group-specific fixed effects model

plot_coeff()

Helper function to plot regression coeffcient

plot_heatmap()

Heatmap of median marker expression

plot_lda()

LDA on marker expression

plot_mds()

MDS on median marker expression

plot_model_selection()

Plot model selection to choose number optimal number of clusters

plot_prcomp()

Plot PCA of subsampled data using ggplot

print(<cytoglm>)

Extact and print bootstrap GLM fit

print(<cytoglmm>)

Extact and print GLMM fit

remove_samples()

Remove samples based on low cell counts

summary(<cytoglm>)

Extact and calculate p-values of bootstrap GLM fit

summary(<cytoglmm>)

Extact and calculate p-values of GLMM fit